General Lab Skills Course

The most recent pandemic due to COVID-19 has certainly had a huge impact on our lives. One of the most affected sectors has been education. Face to face teaching had to be stopped and all teaching was given virtually. Thus, all lectures and practical classes were given online and students had to learn from home. […]

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Quantitation of PHMB in Hand Sanitisers

Polyaminopropyl Biguanide (PHMB) is a broad-spectrum antimicrobial compound found in contact lens cleaning solutions, skin disinfection treatments, and wound dressings, among other things (1). However, this substance has been banned in cosmetics in Europe since 2014. Products such as makeup, creams and body lotions used to contain PHMB as a preservative (2), but PHMB is […]

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HPLC And Mass Spec Testing

Analysis of Lactulose, Rhamnose and Mannitol in Human Plasma

Lactulose Lactulose is a non-absorbable synthetic disaccharide made up of galactose and fructose that is also known as 1,4 beta galactoside-fructose (1). Because the human small intestinal mucosa lacks the enzymes needed to divide lactulose, it reaches the large intestine intact (1). Colonic bacteria convert lactulose to monosaccharides, which are then converted to volatile fatty […]

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analysis of SDMA and ADMA in serum

Analysis of SDMA and ADMA in Serum

Symmetric dimethylarginine (SDMA) and its isomer, asymmetric dimethylarginine (ADMA) are amino acid derivatives which inhibit the body’s ability to produce nitric oxide, a molecule that aids in the maintenance of a healthy endothelium. Moreover, these compounds are formed by intranuclear methylation of L-arginine residues on various regulatory proteins and are released into the cytoplasm following […]

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London laboratory

Bile Salts: An Overview

What are bile salts? Bile salts are a primary component of bile, which is a yellowish-green fluid produced by the liver and stored in the gallbladder.  Function of bile salts Bile salts aid in fat digestion, elimination of toxins and absorption of fat-soluble vitamins such as A, D, E, and K (1). How are they […]

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analysis of nicotinamide in feline plasma

Nicotinamide in Veterinary Practice

What is Nicotinamide? Nicotinamide (also known as Niacinamide) is a form of vitamin B3, which is necessary for the body’s processing of lipids, amino acids, and glucose. A deficiency can have an impact on appetite as well as red blood cell production. Vitamin B3 is an essential vitamin for cats, because they cannot produce it […]

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pesticides in plants

Pesticide Residues in Food & on Plants

The use of pesticides  The agriculture industry faces pressure to protect yields and crops to ensure they can keep up with the high demand and produce large amounts of food. To do this they need to use pesticides (fig.1). Pesticides are used to protect agricultural production and planting from insects, weeds, fungi and other pests. […]

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General Lab Skills Course – A review from our interns

Our general lab skills course is designed to give you the basic skills needed to work in a GLP laboratory environment. You will receive in-house certification once the training is completed. To enroll on this course no previous experience is needed, however depending on your experience the training will be tailored to your needs. What […]

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Alfaxalone in Veterinary Practice

What’s Alfaxalone and its function Alfaxalone (Fig.1) is a neuroactive steroid that has anesthetic properties by acting on the gamma-aminobutyric acid subtype A (GABAA) receptors. It can act as a GABA agonist, when administered in high concentrations or modulate the chloride ion transport across the membrane of neuronal cells when given at low concentrations. Alfaxalone […]

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Mass Spectrometry Training

One of the most used pieces of equipment for analysing a sample is the mass spectrometer. It works by separating ions based on their mass/charge ratio and sending them through a magnetic or electrical field. The theory mass spectrometry (MS) was put forward in the late 1890s, but it wasn’t until the early 20th Centrury […]

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