Things To Avoid: Top 8 Lab Mistakes Made by Students

  Incorrect Labelling  If the labelling is done incorrectly and samples are mixed up as a result, the only thing we can do is repeat the whole experiment, wasting time and products. When using a handwritten label, make sure it is authentic; always add the date of labelling, the expiry date and your initials.    […]

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HPLC

Applications of Chromatography

The identification, measurement, and purification of a specific analyte or chemical are the primary goals of the Chromatographic process. Examinations can be done both quantitatively and qualitatively. HPLC is just one aspect and can be used in the following applications (1): Purifying water  Impurity detection in the pharmaceutical sectors  Trace component pre-concentration  Ligand-exchange  Ion-exchange of […]

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Four Applications of the Mass Spectrometer

The history of mass spectrometry dates back to 1968, when Wolfgang Paul developed the quadrupole mass analyser (1). Mass spectrometry is a technique for determining the mass-to-charge ratio (m/z) of one or more molecules in a sample. These measurements are frequently used to determine the exact molecular weight of sample components. Here are the top […]

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bioanalysis

LC-MS in testing of drugs of abuse

According to national statistics published by the government, between April 2020 and March 2021, 275,896 adults came into contact with drug and alcohol services (1). Testing for drugs of abuse can be  used to a) discover drug abuse; b) monitor someone who has a substance abuse problem; c) detect drug intoxication and d) determine the […]

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HPLC

Types of detectors used in HPLC

In order to quantify and identify the compounds separated in the column, HPLC analysis requires a detector to monitor the compounds themselves. The sort of detector used depends on what is being detected. It’s crucial to think about the type of sample you’ll be analysing before choosing a detector. On some detectors, certain sample types […]

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Bioanalytical Methods – An Overview

The quantitative determination of substances and their metabolites in biological fluids is known as bioanalysis. This technique is employed early in the drug development process to aid drug discovery programmes by providing information on the metabolic fate and pharmacokinetics of compounds in living cells and animals. Techniques used in bioanalysis:  Chromatographic techniques: HPLC (high performance […]

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8 Tips to Improve Your Pipetting Skills

8 Tips to Improve Your Pipetting Skills

When it comes to pipetting, like with most scientific procedures, precision is essential. A minor error can have a significant impact on your results. In this post, we will share 8 tips that will help you improve your pipetting skills.  Pre-wet the pipette tip  Before aspirating for delivery, aspirate and totally expel a quantity of […]

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HPLC

High Performance Liquid Chromatography

High-performance liquid chromatography (HPLC) (Fig.1) is a chromatographic technique that is used to separate a mixture of substances in order to identify, measure, or purify the individual components of the mixture.  How does HPLC work? The sample combination to be separated and evaluated is placed into a stream of mobile phase percolating through a column […]

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bioanalysis

Bioanalysis in Drug Discovery

Drug discovery/development covers different stages until a compound is proven to be effective and safe to use. A new drug’s route from original discovery to the marketplace takes at least ten years, with clinical trials alone requiring six to seven years on average. Each successful medicine is anticipated to cost $2.6 billion in research and […]

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