Four Applications of the Mass Spectrometer

The history of mass spectrometry dates back to 1968, when Wolfgang Paul developed the quadrupole mass analyser (1). Mass spectrometry is a technique for determining the mass-to-charge ratio (m/z) of one or more molecules in a sample. These measurements are frequently used to determine the exact molecular weight of sample components. Here are the top […]

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bioanalysis

LC-MS in testing of drugs of abuse

According to national statistics published by the government, between April 2020 and March 2021, 275,896 adults came into contact with drug and alcohol services (1). Testing for drugs of abuse can be  used to a) discover drug abuse; b) monitor someone who has a substance abuse problem; c) detect drug intoxication and d) determine the […]

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Bioanalytical Methods – An Overview

The quantitative determination of substances and their metabolites in biological fluids is known as bioanalysis. This technique is employed early in the drug development process to aid drug discovery programmes by providing information on the metabolic fate and pharmacokinetics of compounds in living cells and animals. Techniques used in bioanalysis:  Chromatographic techniques: HPLC (high performance […]

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bioanalysis

Bioanalysis in Drug Discovery

Drug discovery/development covers different stages until a compound is proven to be effective and safe to use. A new drug’s route from original discovery to the marketplace takes at least ten years, with clinical trials alone requiring six to seven years on average. Each successful medicine is anticipated to cost $2.6 billion in research and […]

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